Fast , Pseudo - Continuous Arterial Spin Labeling for Functional Imaging Using a Two - Coil System by Luis

2 Abstract A fast, two-coil pseudo-continuous labeling scheme is presented. The new scheme permits collection of a multi-slice subtraction pair in less than three seconds, depending on the subject's arterial transit times. The method consists of acquisition of both the control and tag images immediately after a labeling period that matches the arterial transit time. The theoretical basis of the technique, as well as simulations of the signal during changes in both transit time and perfusion, are presented. Experimental data from functional imaging experiments was collected to demonstrate the technique and its characteristics.